Research in the Arandjelovic Lab is focused on the process of apoptotic (dying) cell clearance, also known as efferocytosis (from Greek effero, meaning to “bury” or “take to the grave”). Apoptotic cells are frequently observed at sites of ongoing inflammation, and their inefficient removal can lead to secondary necrosis and the release of their cellular contents, which can further fuel the inflammatory process. At the same tme, metabolites released by apoptotic cells, also referred to as ‘good-bye’ signals, elicit cellular responses that actively promote resolution of inflammation and tissue regeneration, which is essential for the maintenance of immune ‘silence’.